Overview
When Billy finds his "son" Jeff the Spider lying in his bed with "Spider Pox", he goes to Mandy for help to get rid of the giant spider. While ignoring Billy, the next morning Mandy awakens afflicted by Spider Pox too, developing four additional arms and the ability to produce spider web. Mandy's condition progresses and she completely turns into a giant spider, who captures Billy's parents and Grim. Grim tells Billy that, to cure Mandy, he must use the venom of the spider that infected her. While Billy successfully gives Mandy Jeff's venom, he also carried the virus and infected the people of the city, who have all turned into spiders.
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6 - 1Billy Ocean January 06, 2006
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6 - 2Hill Billy January 06, 2006
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6 - 3Keeper of the Reaper January 13, 2006
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6 - 4The Love That Dare Not Speak Its Name January 20, 2006
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6 - 5Major Cheese January 20, 2006
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6 - 6Modern Primitives January 27, 2006
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6 - 7Giant Billy and Mandy All Out Attack January 27, 2006
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6 - 8The Wrongest Yard March 20, 2006
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6 - 9Druid, Where's My Car? March 20, 2006
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6 - 10Herbicidal Maniac March 21, 2006
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6 - 11Chaos Theory March 21, 2006
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6 - 12A Grim Day March 22, 2006
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6 - 13Pandora's Lunch Box March 22, 2006
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6 - 14Billy and Mandy vs. the Martians March 23, 2006
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6 - 15Dumb-Dumbs and Dragons May 12, 2006
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6 - 16Fear and Loathing in Endsville May 12, 2006
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6 - 17Dad Day Afternoon June 05, 2006
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6 - 18Scary Poppins June 05, 2006
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6 - 19Hurter Monkey July 10, 2006
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6 - 20Goodbling and the Hip-Hop-Opotamus July 10, 2006
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6 - 21Spidermandy July 24, 2006
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6 - 22Be A-Fred, Be Very A-Fred July 24, 2006
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6 - 23The Crass Unicorn August 09, 2006
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6 - 24Billy & Mandy Begins August 09, 2006